Grand Theft Auto IV's deeper meaning circulates around Niko's own philosophy, and his clear, blunt critiques of American culture and life in general make the deeper ideas much easier to see and understand.
The very first dialogue by Niko in the very first trailer for the game sets up the first notable protagonist to be from another country other than the United States, Niko Bellic, to enter the United States of America and make more critical analysis of American culture than previous main characters have done.